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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa14c61018c364e853d498a38c7d1afbf3bff4aa287b5f0b79cfb698625fc39' 
  AND token = '+MC+RAMxXQ489c19deOjhq6YPTNDi0gADIid91/YJj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}