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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '829ed51495e723a6cd1849abb7522877b9481ad5c5e0a4bb87968b784a51cb41' 
  AND token = 'tIgzYqUk+9z39caOh9b/s8b5NAcR1pCqARtZa3Mmmo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}