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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d52a9ea7c241c2eecbc37c1f4c017e8fe2722f83c3a94e7e45f950334189793' 
  AND token = 'rBKrDToADwzYxVMW60L5HEbYWVmY2jvA7GTlufZ7Hyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}