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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d098b7e2b15182e599da456ae9f746306e672f13fc62088221e5f37f55f8bd4' 
  AND token = 'NQIByoB/LFEvM7yys7ruPPJaTMAr7IQqwN7ZhcA+PeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}