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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3857de8e4867e0e5a914a60ba61e82ef655af5daeee68c21b0b8d3357fb5f140' 
  AND token = 'RHIWA7EKK6m6KaPv00k9647xWax2rh7BlS6gIFAw4fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}