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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc889a972504d6d1e776695ca702b6c938231a1c4da11725733f2b0af6c5f912' 
  AND token = '0B6eRjkfWWtTKDmC8TPLafKhzfnTaUGXn8Vj2kbD6iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}