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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a916454d027f4733217d21e622bec4a260042c34af1d8ae9f8d6565848d20a' 
  AND token = '1+MG04XTojijVmSCuQxxLI3GkzsbHvHya9vCGoduI0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}