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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b6fca4587bf066b3ae61a49c38ccc12a6ae01e86e77b71d1208f2865521003' 
  AND token = '4Sbx9czTGRvPpQuTryFkZF0U/YgZB8Z6A6G3EKtdKUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}