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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3dca8d76b51e3aa095e33a47fdecad764c31d7c9150e4aa72f13c2c6de207a' 
  AND token = 'j7fdIvRFjJZ6vBZWN/+D1s4JsH9BXRUL/49NY2cmNm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}