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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7b048a838e58b0cb4267613653bc6aead4f23833987c266d99a79335980008' 
  AND token = '3z4DgVN9/L0MAeGgW05vYipXkZPHYdR4FZGk75qi+9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}