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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657bf00de5586d84b929f81f14ea241940b4048606e7bf371de9f6720254d0d8' 
  AND token = 'iiuy0vM56qo1UJ5ksvMzKRe/zdS8GxT65EPFeKcOVww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}