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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944e09b769bdef7d434f964750913c7e38fb773ab19dab3a9f3e236d1a023a38' 
  AND token = 'M3xRTjW1M7BEghDs3aNoznhI8DdXhLbaUddnJo9RN+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}