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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16fb303823f09b00bd0c93e94db7c0880c2ae242a8f76e3be5d0bc1d26692ce8' 
  AND token = 'ng3VSD4oqRmPWJVaNufoFkPVYHpjxKH6gj8OFEOudOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}