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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286bc815b74cfc0cfdb32e86aef1d31bf8178e6a1cade708d810ead7c20adfad' 
  AND token = 'DuS4NdKkQg8IJoIYZDxcFJxKuUWNqWonTn/6b03cQTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}