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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4712d7e9d3b4d41d419783bde1b53d499684e86021d064b0e5161ea87c26a4' 
  AND token = 'A1O8gOEp0j+Fx3E0UP4IuCqPNQ3gRaL73cUIm7+/InI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}