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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d41934487d13c2a95cc6f89fe296423f45e7c865726b969ff459762fad8fc55' 
  AND token = 'uoD1hEW6uzXAW5ErE35UCD2nmvIPjqB0kzu29T1U5vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}