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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8499820cb8165e5aa11abdf6f2dc4f9ceff5f370b06cc169299003de574162f' 
  AND token = 'VhcLzfy+D7fknJ5p9OL35H1rCnSThfzi4QnJ49Y2b2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}