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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b7bedf22b0a9b8fd116cdb41ca72168cf8bf71aa8c71d086d2d53178815829' 
  AND token = 'FZsy9Dq4mb3FwEY+4GtGC8MBZOBBxD7jEA47qRnezd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}