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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b1c3ed0c5cf3397fdf3510b36df1e45b30ecb2b7254412d444596b800f1e0bd' 
  AND token = '+1H8DUvDJtUA+hySVy7tYoNiBkuPC1bZF332lzXAU9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}