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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d7b284a463c486dc2f51fad86314ed65e686bb7429e932484346f9ec2ee12f' 
  AND token = 'Wy6i/+uEsQaZXtSpR5RN0as4KbG6eJY2VXu19R3hQA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}