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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af33fa99f5ddad78abb3a1a7f01d13cd733d63f3e303484823221bb3ca2857bd' 
  AND token = 'oeYejvjnYsinawvGUFMchWhfD8Z9Tyiy6PfvhWKVrgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}