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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c52ee0c57673d6b81c0f75cc2a4bb509c38774979e16122672600b8c8ac487e' 
  AND token = 'EiLj/q/puvUB2C2Opo/68m33KuOzBaXS13rB4EFQR5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}