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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455ae976008b11171eadaf9c933dd52494741da891e75acaa9c9888b5515b143' 
  AND token = 'rH/aIN/COutYNM/pSbVC/YcosV53kDYuHLcZCqvxiWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}