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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5348665c266d07902054ff3f9c03d489b8f6fe145b4e684f104d62b3bddd9e33' 
  AND token = 'hsgi5wtDZvU7k9HU+WeW82pG4WskouuIjZ1GUpFAC+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}