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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756df9b11543e72d1abb18b5f9346215a88d82f2ccd31de82eb09e65f25422f6' 
  AND token = 'X7tvqgo1/uk2FrAh7MckAeQOzhho2LF4eMP5nJHFn/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}