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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346e5ce51517c136bf0fd424bd4212d75baa8a908ac456c5bc70f783939ffbca' 
  AND token = 'IzWPP0Q9j/TaUWlNTEUmKCuBcf1BvVzJ5Qebyh33t4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}