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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2033457a5a824352a07e9d4a1f16e1f2cda98b4876453751dc3c8e53418b3a84' 
  AND token = 'RmktYOunXmZNVt0duS/rDX/poIHyY72/VW/ilRB6Upw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}