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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3df3dab66e5fff4c2e49affe3418dcd7cac5f3da0f71b43769a15a46025e26f' 
  AND token = '5/ufGXO+th6xYWcAMJNimdYy/3wudQ6blZYvMOl4Yy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}