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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9dde765ad73011aa85f755d86794cae330c30557d8d433f688f0c5f661e1cc' 
  AND token = '+XNpz5GFgxjAT2ydEqdKE+V4X6QMEWghqkSuXSqZGuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}