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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a485910cd0ddc32e1987320215745ff7bd713acdc84dd5ca0527a404eb8cc5a2' 
  AND token = '+ZIZhNIH8lMw5OjN2dnHQCvd11bPue/VfBs+UhOp45g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}