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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001a8a1cc93ffb577d86b86b4f43f5fea35c78e56f82217e7e18a4f829a8bafa' 
  AND token = 'y/Z3L0NWmnQQlbml9LwluPSX0e1s/oiaH2ePdnasWX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}