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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd7c15784f7f44beb7c1155fb47201ff6f12256457c7598d051e5e6142f1ced' 
  AND token = 'MscwBfzOGSUttxO1hTevFR80FEQCjiy383vcwhwb8N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}