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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5538edbbf6cbcdc15de1bd211e29c4560a41516357e4cb341b1a82a5050f4f7' 
  AND token = 'YjZ1IzPAKWXEP4MQnTllbVU/R9kDAO2kLO/i8WHwbqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}