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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '629aa380a7de50254379622ef6c243442c88370afd2857038c83e6368c50f304' 
  AND token = 'Io25doW75Ve29Bh7qZnSsa0CP6gkMT3fEQO1Mb+nXtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}