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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5c3c7583ee606c6e3012d4937767a6806e689fce01cce2d367657c40190ef0' 
  AND token = 'ctDbs5R5KoPbMHkAOkzy2cEj2a07sbHWXXEqVjBFg2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}