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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1271f846979ab1a40560cbb47ac38524e60dd57d9a4853529c02147e3f51df9c' 
  AND token = 'A1Wd1xvM9q5qCdrpi4/OUDY5gi5KRc0UEA91LzcrQbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}