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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a427f1f39e43b4a801e29bcdf7c8f888ce811cb89797c5cd1a43afbce7fc500a' 
  AND token = 'yu4oZnch87oMu3Zz/JWVooJsw8n7iZ4e+Bjs8Qr542Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}