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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01725478b2c006f475b32268407f3e1018940864f0aa9fe70d50ca14ac1d1528' 
  AND token = '4PhzkXt4o2Kw0ps9jqBZt46KAPee3Rjk+Ylw0H+WT24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}