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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a474449fb8077fbdc016d3e050a60e1b6bac04bb84bf6c2f4cda8b500fb0c4' 
  AND token = '2Q63Uv4KuYEWfQPZYJoOxRrgn66THQttlape/J9eg14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}