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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b47a6306ee356e4d1579b5f51b123531606acfc3727138dbcc00ce7a6991401' 
  AND token = 'Rv4tDF+hQ6D2bbpAEtiWKUfmAnmlwB+dVwdzFgO05CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}