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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4747a29367ed8f76b4dea38377b4129840c80917527d60b0a2bfcde88ce338' 
  AND token = 'crO1rI5fX9O5S61LgZGR4N6+qBOBjDrtVs8H5Z5wTQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}