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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ce5b84bb4b96b4fb229d4c1d94da5f555f7b225559b9725159128cf9018c0fa' 
  AND token = 'clSK5J93Kz7psXRl1UlmRv6JCLnvJUENy27iBQntLxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}