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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd76cf2c03fe290361adc3393d62657b14e60717f65c1be6ecfc954c9d2a56cb' 
  AND token = 'Os2m9Gh2bXq7zNU2xG3hBbM9gaPD2Q5caOe5JjNRpnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}