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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '338c38c206d3061db6496d7f74fc8faa5c33c2ac53cb1104441539e84122c75b' 
  AND token = 'l6G0009YDfPRliV60iXNzubfry0d7HRMzl4l7waTt6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}