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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59aa9cd11a72e5ae9a74a4ab54e75472887703b0b75ef8aa49bc93062f9418ca' 
  AND token = 'U1alwWYd7PitucA1dISjPcXnvdi+gtbDPRyR+byOSjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}