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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e56f28768ac3b77592ecc6ee5061379b0a5f10300f28e96fa6cac15a23215493' 
  AND token = 'UzXY5qrLa1oZWyjR5Ujd1THOWewQ23MCQ3hSUtg2gTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}