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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '021b6274ee6b66e3780df5cd755cacddb820bbbd5524e6150c314041386e48f5' 
  AND token = 'pJiAHAwfLRe6du0645RD2OS1vpabTOYVqCRD7G6R/s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}