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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3d0148943f4a85d11aec84671822508d0b03467b9fd522b56871b5c4ad5e53' 
  AND token = 'a850IRcfP9yScCO79LyPoNSvzp/B+7EhZW2MohAG79M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}