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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481dfa0c7199638b63571ca7c744b8acde797d646b435780b1fb2340497d0a23' 
  AND token = 'kXbumM9hn0/6HkR5EdwOM/7O7APCTVQN6p0pEm9gqd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}