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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c37e47e2cb8aab90bbdb818bbd9587b0a5833804d7b1e13c7127ec1a1071649' 
  AND token = '9IthA98YVYeH+4Ead2L526ds1E17UhaMBAhuOOWivuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}